RETRACTED: Probing the MicroRNA and Small Interfering RNA Pathways with Virus-Encoded Suppressors of RNA Silencing
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چکیده
منابع مشابه
Probing the MicroRNA and Small Interfering RNA Pathways with Virus-Encoded Suppressors of RNA Silencing W
In plants, small interfering RNAs (siRNAs) and microRNAs (miRNAs) are effectors of RNA silencing, a process involved in defense through RNA interference (RNAi) and in development. Plant viruses are natural targets of RNA silencing, and as a counterdefensive strategy, they have evolved highly diverse silencing suppressor proteins. Although viral suppressors are usually thought to act at distinct...
متن کاملProbing the microRNA and small interfering RNA pathways with virus-encoded suppressors of RNA silencing.
In plants, small interfering RNAs (siRNAs) and microRNAs (miRNAs) are effectors of RNA silencing, a process involved in defense through RNA interference (RNAi) and in development. Plant viruses are natural targets of RNA silencing, and as a counterdefensive strategy, they have evolved highly diverse silencing suppressor proteins. Although viral suppressors are usually thought to act at distinct...
متن کاملSmall interfering RNA; principles, applications and challenges--
Gene silencing using RNAi (RNA interference), has recently been used as a successful laboratory technique in determining the function and control of gene expression and provides a wide range of applications in molecular biology and gene therapy. RNAi is a method of suppressing gene expression. In this direction, a single-stranded RNA molecule of about 21–23 nucleotides, called siRNA (small inte...
متن کاملViral Suppressors of RNA Silencing Hinder Exogenous and Endogenous Small RNA Pathways in Drosophila
BACKGROUND In plants and insects, RNA interference (RNAi) is the main responder against viruses and shapes the basis of antiviral immunity. Viruses counter this defense by expressing viral suppressors of RNAi (VSRs). While VSRs in Drosophila melanogaster were shown to inhibit RNAi through different modes of action, whether they act on other silencing pathways remained unexplored. METHODOLOGY/...
متن کاملHighly Abundant Small Interfering RNAs Derived from a Satellite RNA Contribute to Symptom Attenuation by Binding Helper Virus-Encoded RNA Silencing Suppressors
Satellite RNAs (satRNAs) are always found accompanying a helper virus (HV) upon which they are functionally dependent for replication (catalyzed by an RNA replicase coded in part by the HV) and transmission (following encapsidation by the HV coat protein) (Palukaitis, 2016). Most satRNAs have a small size, lower than 700 nt, and do not encode any protein, with the Y satRNA (Y-Sat) of cucumber m...
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ژورنال
عنوان ژورنال: The Plant Cell
سال: 2004
ISSN: 1040-4651,1532-298X
DOI: 10.1105/tpc.020719